3-Chloro-4-fluorophenylzinc iodide solution 0.5 in THF
3-Chloro-4-fluorophenylzinc iodide
CAS: 312624-19-4
Molecular Formula: C6H3ClFIZn
3-Chloro-4-fluorophenylzinc iodide solution 0.5 in THF - Names and Identifiers
3-Chloro-4-fluorophenylzinc iodide solution 0.5 in THF - Physico-chemical Properties
| Molecular Formula | C6H3ClFIZn |
| Molar Mass | 321.83 |
| Density | 1.009g/mLat 25°C |
| Boling Point | 65°C |
| Flash Point | 1°F |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
| Storage Condition | 2-8°C |
3-Chloro-4-fluorophenylzinc iodide solution 0.5 in THF - Risk and Safety
| Risk Codes | R19 - May form explosive peroxides R22 - Harmful if swallowed R36/38 - Irritating to eyes and skin. R40 - Limited evidence of a carcinogenic effect R36/37 - Irritating to eyes and respiratory system. R14 - Reacts violently with water R11 - Highly Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33 - Take precautionary measures against static discharges. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2056 3/PG 2 |
| WGK Germany | - |
| Hazard Note | Flammable |
3-Chloro-4-fluorophenylzinc iodide solution 0.5 in THF - Introduction
Iodide is an organozinc compound with the chemical formula C6H4ClFZnI. It is a white solid, stable at room temperature. It has a certain organic solvent solubility, can be dissolved in chlorinated solvents (such as dichloromethane, chloroform).
iodide is mainly used as an alkyl zinc reagent in organic synthesis reactions and can react with other organic compounds to form carbon-carbon bonds. It is an important organometallic reagent commonly used in the synthesis of carbon-carbon bonds for the construction of organic molecules, such as the introduction of aromatic compounds and the synthesis of heterocycles.
The method of preparing iodide is usually obtained by first preparing a 3-chloro-4-fluorophenyl copper compound and then reacting it with zinc iodide. The specific preparation method can be the preparation of 3-chloro-4-fluorophenyl copper compound by the method of Grignard reagent, and then the reaction with zinc iodide to generate iodide. The preparative reaction needs to be carried out under dry and inert atmosphere.
Regarding safety information, iodide is an organometallic reagent, and attention should be paid to safe operation when using it. It is irritating to the skin and eyes, avoid contact with skin and eyes. Use in a well-ventilated laboratory environment and wear personal protective equipment, such as gloves and glasses. At the same time, it is also a flammable substance and needs to be kept away from fire and heat sources and stored properly. Observe local environmental safety regulations when using or disposing of waste.
iodide is mainly used as an alkyl zinc reagent in organic synthesis reactions and can react with other organic compounds to form carbon-carbon bonds. It is an important organometallic reagent commonly used in the synthesis of carbon-carbon bonds for the construction of organic molecules, such as the introduction of aromatic compounds and the synthesis of heterocycles.
The method of preparing iodide is usually obtained by first preparing a 3-chloro-4-fluorophenyl copper compound and then reacting it with zinc iodide. The specific preparation method can be the preparation of 3-chloro-4-fluorophenyl copper compound by the method of Grignard reagent, and then the reaction with zinc iodide to generate iodide. The preparative reaction needs to be carried out under dry and inert atmosphere.
Regarding safety information, iodide is an organometallic reagent, and attention should be paid to safe operation when using it. It is irritating to the skin and eyes, avoid contact with skin and eyes. Use in a well-ventilated laboratory environment and wear personal protective equipment, such as gloves and glasses. At the same time, it is also a flammable substance and needs to be kept away from fire and heat sources and stored properly. Observe local environmental safety regulations when using or disposing of waste.
Last Update：2024-04-10 22:29:15
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